Depending on where you got this game, controls may be an issue.
Default control scheme goes something like this:
Movement: Arrow Keys
Strafing : < and >
Look Up/ Look Down: PgUp and PgDown
Fire Weapon: Ctrl
Run Mode: ~ (tilde)
Jump: A
Crouch: Z
Display Bindings: H
Mouse: Adventure game stuff, and RMB moves you forward.
If you bought it from GoG or Steam, you'll need to get a patch to enable key-bindings.
Some pretty clear instructions are here
http://shadowcat.freehosting.net/roth_patch.html
What it boils down to is replacing the exe and one other file with those provided above, and navigating through a series of "Missing Text" menus to rebind. It's a hack, but it works.